Herpes zoster
https://en.wikipedia.org/wiki/Shingles
☆ Mune 2022 Stiftung Warentest mhedzisiro kubva kuGermany, kugutsikana kwevatengi neModelDerm kwakangodzikira zvishoma pane nekubhadharwa kwe telemedicine kubvunzana. relevance score : -100.0%
References
Herpes Zoster and Postherpetic Neuralgia: Prevention and Management 29431387Shingles, inokonzerwa nekugadzirisazve varicella zoster virus inokonzera chickenpox, inobata vanhu vanosvika mamiriyoni e1 gore negore muUnited States, ine ngozi yehupenyu hwe30%. Avo vane immune system isina simba vanonyanya kukurumidza kugadzira shingles, vane zviratidzo zvinowanzotanga ne malaise, kutemwa nemusoro, uye fivha yakapfava, ichiteverwa nekusajairika kwekunzwa kweganda mazuva mashoma kusati kwaonekwa. Uku kuputika, kazhinji kuoneka munzvimbo chaiyo yemuviri, kunofambira mberi kubva kune mablister akajeka kusvika kune maronda akaoma kwevhiki kusvika kumazuva gumi. Kurapwa nekukurumidza nemishonga inorwisa mavhairasi (acyclovir, valacyclovir, or famciclovir) mukati memaawa makumi manomwe nemaviri ekutanga kwepundu kwakakosha. Postherpetic neuralgia, dambudziko rinowanzozivikanwa nekurwadziwa kwenguva refu munzvimbo yakakanganiswa, inobata anenge mumwe muvarwere vashanu uye inoda kuramba ichitungamirirwa nemishonga yakadai segabapentin, pregabalin, kana mamwe maantidepressants, pamwe chete nemishonga inonzi lidocaine kana capsaicin. Kudzivirira varicella zoster virus kunokurudzirwa kuvanhu vakuru vane makore makumi mashanu zvichikwira kuderedza njodzi yeshingles.
Shingles, caused by the reactivation of the varicella zoster virus responsible for chickenpox, affects around 1 million people annually in the United States, with a lifetime risk of 30%. Those with weakened immune systems are significantly more prone to developing shingles, with symptoms typically starting with malaise, headache, and a mild fever, followed by unusual skin sensations a few days before the appearance of a rash. This rash, usually appearing in a specific area of the body, progresses from clear blisters to crusted sores over a week to ten days. Prompt treatment with antiviral medications (acyclovir, valacyclovir, or famciclovir) within 72 hours of rash onset is crucial. Postherpetic neuralgia, a common complication characterized by prolonged pain in the affected area, affects about one in five patients and requires ongoing management with medications such as gabapentin, pregabalin, or certain antidepressants, along with topical agents like lidocaine or capsaicin. Vaccination against the varicella zoster virus is recommended for adults aged 50 and above to reduce the risk of shingles.
Epidemiology, treatment and prevention of herpes zoster: A comprehensive review 29516900Herpes zoster inowanzoitika muvanhu vane makore makumi mashanu zvichikwira, avo vane immune system isina simba, uye avo vanotora immunosuppressant mishonga. Zvinokonzerwa nekuvandudzwa kwehutachiona hwevaricella-zoster, hutachiona humwe hunokonzera chickenpox. Zviratidzo zvakadai sefivha, kurwadziwa, uye kukwenya zvinowanzotangira kuoneka kwechimiro chepundu. Dambudziko rinowanzoitika ndeye post-herpetic neuralgia, iyo inoramba ichirwadza tsinga mushure mekuputika kwapera. Izvo zvinokonzeresa uye zvinonetsa zvine chekuita neherpes zoster zvinosiyana zvichienderana nezera, hutano hwekudzivirira muviri, uye nguva yekutanga kurapwa. Kudzivirira kune vanhu vane makore makumi matanhatu zvichikwira kwakaratidza kuderedza zvakanyanya kuitika kweherpes zoster uye post-herpetic neuralgia. Kutanga mishonga inorwisa mavhairasi uye zvinoderedza marwadzo mukati meawa 72 ekukurumidza kutanga kunogona kuderedza kuomarara uye matambudziko eherpes zoster uye post-herpetic neuralgia.
Herpes zoster tends to occur more frequently in people aged 50 and older, those with weakened immune systems, and those taking immunosuppressant medications. It's triggered by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. Symptoms like fever, pain, and itching commonly precede the appearance of the characteristic rash. The most common complication is post-herpetic neuralgia, which is persistent nerve pain after the rash clears up. The risk factors and complications associated with herpes zoster vary depending on age, immune health, and timing of treatment initiation. Vaccination for individuals aged 60 and above has been shown to significantly reduce the occurrence of herpes zoster and post-herpetic neuralgia. Starting antiviral medications and pain relievers within 72 hours of rash onset can lessen the severity and complications of herpes zoster and post-herpetic neuralgia.
Prevention of Herpes Zoster: A Focus on the Effectiveness and Safety of Herpes Zoster Vaccines 36560671 NIH
Miedzo yekiriniki isati yatenderwa inoratidza kuti mhenyu yekudzivirira yezoster inoshanda zvakatenderedza makumi mashanu kusvika makumi manomwe muzana, nepo recombinant vaccine ichiita zvirinani, kubva pa90 kusvika 97%. Muzvidzidzo zvepasirese, vanotsigira zvakawanikwa muyedzo, zvichiratidza kuti jekiseni mhenyu rinenge 46% inoshanda, nepo recombinant iri kutenderera 85%.
The pre-licensure clinical trials show the efficacy of the live zoster vaccine to be between 50 and 70% and for the recombinant vaccine to be higher at 90 to 97%. Real-world effectiveness studies, with a follow-up of approximately 10 years, were reviewed in this article. These data corroborated the efficacy studies, with vaccine effectiveness being 46% and 85% for the live and recombinant vaccines, respectively.
Chickenpox, inonziwo varicella, inokonzerwa nehutachiona hwekutanga nehutachiona, hunowanzoitika panguva yehuduku kana kuyaruka. Kana chickenpox ichinge yapora, hutachiona hunogona kuramba husina kushanda (hwakarara) mumasero etsinga dzevanhu kwemakore kana makumi emakore, mushure mezvo hunogona kuita zvakare. Herpes zoster mhedzisiro kana iyo dormant varicella virus yaitwa zvakare. Ipapo utachiona hwacho hunoenda nemigumo yetsinga muganda, huchibudisa matuzu. Munguva yekuputika kwe herpes zoster , kuratidzwa kune varicella virus inowanikwa mu herpes zoster blisters inogona kukonzera chickenpox kune mumwe munhu asati aita chickenpox.
Zvikonzero zvekukonzeresa hutachiona hwehutachiona hunosanganisira kuchembera, kusashanda zvakanaka kwekudzivirira muviri, uye kubata chickenpox isati yasvika mwedzi gumi nemasere. Varicella zoster virus haina kufanana neherpes simplex virus, kunyangwe vese vari vemhuri imwechete yeherpesviruses.
Herpes zoster majekiseni anoderedza njodzi ye herpes zoster ne50% kusvika 90%. Iyo zvakare inoderedza mitengo ye postherpetic neuralgia, uye, kana herpes zoster ikaitika, kuoma kwayo. Kana herpes zoster ichikura, mishonga inorwisa mavhairasi yakadai seaciclovir inogona kuderedza kuoma uye nguva yechirwere kana yakatanga mukati maawa makumi manomwe nemaviri ekuonekwa kwepundu.
○ Kurapa
Kana maronda ari kupararira nekukasira, ona chiremba wako nekukasira kuti uwane mushonga weantiviral.
Zvose zviri zviviri antiviral mishonga uye neuralgia mishonga inodiwa. Unofanira kuzorora uye kurega kunwa doro.
#Acyclovir
#Fancyclovir
#Valacyclovir
#Gabapentin
#Pregabalin